Format

Send to:

Choose Destination
See comment in PubMed Commons below
Account Res. 2008 Jul-Sep;15(3):152-67. doi: 10.1080/08989620802194384.

Industry-sponsored ghostwriting in clinical trial reporting: a case study.

Author information

  • 1Department of Philosophy, California State University, Northridge, California 91330, USA. leemon.mchenry@csun.edu

Abstract

In this case study from litigation, we show how ghostwriting of clinical trial results can contribute to the manipulation of data to favor the study medication. Study 329 for paroxetine pediatric use was negative for efficacy and positive for harm. Yet the ghostwritten publication from this study concluded that paroxetine provided evidence of efficacy and safety and continues to be influential. Despite the role of named authors in revisions of the manuscript, the sponsor company remained in control of the message.

PMID:
18792536
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Write to the Help Desk