Abstract
Natural phosphate doped with iodine or potassium iodide is an active catalyst for the one-pot synthesis of acyclonucleosides. To demonstrate the utility of the new catalyst system, the highly important antiviral drug acyclovir was directly and regioselectively obtained from NAcG with no byproducts.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acyclovir / chemical synthesis*
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Antiviral Agents / chemical synthesis*
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Catalysis
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Iodine / chemistry
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Molecular Structure
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Nucleosides / chemical synthesis*
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Phosphates / chemistry*
Substances
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Antiviral Agents
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Nucleosides
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Phosphates
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Iodine
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Acyclovir