Cancer among potash workers in Saskatchewan.
Canadian Institute of Health and Safety in Agriculture, Department of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
OBJECTIVE: To investigate what factors contribute to the increased risk of developing cancer among potash mine workers. METHODOLOGY: Data on 1434 male potash workers based on a nested case-control (Cases: potash workers whose personal identifiers matched those of an individual registered with the Saskatchewan Cancer Agency, Controls: all other potash workers) study design were analyzed. RESULTS: An occupational history of farming (RR [95% CI =]: 1.79 [1.26, 2.55]), presence of pleurisy at baseline [1.90 (1.07 to 3.40)], previous hard rock mining experience [1.74 (1.01 to 3.00)], and age statistically significantly elevated the risk of becoming a case. Smoking status was an effect modifier for the relationship between any respiratory disease at baseline and cancer. CONCLUSIONS: Age; previous occupational history of farming and rock mining; interaction between any respiratory disease and smoking status were positively associated with the development of cancer.
PMID: 18784552 [PubMed - indexed for MEDLINE]