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J Med Case Rep. 2008 Sep 9;2:295. doi: 10.1186/1752-1947-2-295.

Symplastic scrotal leiomyoma: a case report.

Author information

  • 1Department of Urology, Royal Cornwall Hospital, Truro, UK. indianajoe@gmail.com

Abstract

INTRODUCTION:

Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case.

CASE PRESENTATION:

We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up.

CONCLUSION:

Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up.

PMID:
18782437
[PubMed]
PMCID:
PMC2542396
Free PMC Article

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