Scand J Immunol. 2008 Oct;68(4):363-70.

Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer.

Hetland G, Johnson E, Lyberg T, Bernardshaw S, Tryggestad AM, Grinde B.

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Department of Immunology and Transfusion Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. geir.hetland@medisin.uio.no

Abstract

Agaricus blazei Murill (AbM) is an edible, medicinal mushroom of Brazilian origin. It is used traditionally against a range of diseases, including cancer and chronic hepatitis, and has been cultivated commercially for the health food market. AbM has recently been shown to have strong immunomodulating properties, which has led to increasing scientific interest. In this article, we review current knowledge as to the immunological properties of AbM, and its possible clinical use in connection with infections and cancer. We also present some novel findings, which point to highly different biological potency between AbM extracts of different source and manufacturing.

PMID:: 18782264; [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation. [Adv Pharmacol Sci. 2011]
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Hetland G, Johnson E, Lyberg T, Kvalheim G. Adv Pharmacol Sci. 2011; 2011:157015. Epub 2011 Sep 6.
An extract of the medicinal mushroom Agaricus blazei Murill can protect against allergy. [Clin Mol Allergy. 2009]
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