Reduced-representation methylation mapping. [Genome Biol. 2008]

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1: Genome Biol. 2008;9(8):231. Epub 2008 Sep 1. Links

Reduced-representation methylation mapping.

Jeddeloh JA, Greally JM, Rando OJ.

Roche NimbleGen Inc, Research and Development, 500 S. Rosa Rd, Madison, WI 53719, USA. jeffrey.jeddeloh@roche.com

The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.

PMID: 18771577 [PubMed - indexed for MEDLINE]

PMCID: PMC2575507 [Available on 2009/09/01]

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