This study examined sex differences in alcohol-associated smoking urge and smoking patterns to elucidate factors contributing to the co-use of alcohol and cigarettes. Participants were 39 (22M, 17F) binge-drinking tobacco chippers. Although men and women showed similar alcohol-smoking patterns and similar alcohol-induced smoking urges, a positive association between these factors was observed only in men. The lack of relationship in women suggests that co-use of these substances may be due to exteroceptive factors beyond the pharmacological effects of alcohol potentiating smoking urge.