Curr Opin Neurol. 2008 Oct;21(5):555-62.

Intravenous immunoglobulins in the treatment of immune neuropathies.

Kieseier BC, Meyer Zu Hörste G, Lehmann HC, Gold R, Hartung HP.

Source

Department of Neurology, Heinrich-Heine-University, Duesseldorf, Germany. bernd.kieseier@uni-duesseldorf.de

Abstract

PURPOSE OF REVIEW:

The aim of this review is to describe the value of high-dose polyclonal intravenous immunoglobulins as a treatment option in autoimmune disorders affecting the peripheral nervous system.

RECENT FINDINGS:

A randomized placebo-controlled trial in patients with chronic inflammatory demyelinating polyradiculoneuropathy revealed short-term and long-term efficacy and safety of intravenous immunoglobulins as a treatment option for the chronically inflamed peripheral nervous system. Case reports suggest that the subcutaneous administration of immunoglobulins may represent a convenient alternative.

SUMMARY:

Intravenous immunoglobulin represents an effective and safe treatment option in patients with autoimmune-mediated diseases affecting the peripheral nerves.

PMID:: 18769249; [PubMed - indexed for MEDLINE]

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Cited by 3 PubMed Central articles

Pathogenesis and treatment of immune-mediated neuropathies. [Ther Adv Neurol Disord. 2009]
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