Dendrogram showing the similarity of KHM-1 to other MBLs. KHM-1 and MBLs from a variety of organisms were tested. The dendrogram was created with the ClustalW program. Branch lengths correspond to the number of amino acid exchanges of the following MBL proteins (GenBank accession numbers, source organism) of BcII (P04190, from Bacillus cereus), BlaB (CAA65601, from Elizabethkingia meningoseptica), CcrA (P25910, from Bacteroides fragilis), CGB-1 (AAL55263, from Chryseobacterium gleum), EBR-1 (AAN32638, from Empedobacter brevis), GIM-1 (CAF05908, from Pseudomonas aeruginosa), IMP-1 (AAB30289, from Serratia marcescens), IND-1 (AAD20273, from Chryseobacterium indologenes), JOHN-1 (AAK38324, from Flavobacterium johnsoniae), MUS-1 (AAN63647, from Myroides odoratimimus), SIM-1 (AAX76774, from Acinetobacter baumannii), SPM-1 (CAD37801, from P. aeruginosa), TUS-1 (AAN63648, from Myroides odoratus), Uvs123 (AAP70377, from uncultured bacterium), and VIM-1 (CAB46686, from P. aeruginosa).