Clin Infect Dis. 2008 Oct 1;47(7):931-4.

Intranasal transmission of hepatitis C virus: virological and clinical evidence.

Aaron S, McMahon JM, Milano D, Torres L, Clatts M, Tortu S, Mildvan D, Simm M.

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Molecular Virology Division, St. Luke's-Roosevelt Institute for Health Sciences/Columbia University.

Abstract

Intranasal transmission of hepatitis C virus (HCV) via contaminated drug-sniffing implements is a potential but unconfirmed source of viral infection. We demonstrate the virological plausibility of intranasal transmission by confirming that blood and HCV RNA are present in the nasal secretions and drug-sniffing implements of HCV-infected intranasal drug users recruited from a community health clinic in New York City.

PMID:: 18764772; [PubMed - indexed for MEDLINE]

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Research Support, N.I.H., Extramural

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R21 DA019834/DA/NIDA NIH HHS/United States

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