Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Autism Dev Disord. 2009 Mar;39(3):395-404. doi: 10.1007/s10803-008-0636-9. Epub 2008 Aug 28.

Positive effects of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity.

Author information

  • 1School of Social and Family Dynamics, Arizona State University, Box 873701, Tempe, AZ 85287-3701, USA. Laudan.Jahromi@asu.edu

Abstract

This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data. Participants were 33 children (29 boys) between the ages of 5 and 13 years who participated in a four-week crossover trial of placebo and increasing doses of methylphenidate given in random order each for one week. Observational measures of certain aspects of children's social communication, self-regulation, and affective behavior were obtained each week. A significant positive effect of methylphenidate was seen on children's use of joint attention initiations, response to bids for joint attention, self-regulation, and regulated affective state. The results go beyond the recent literature and suggest that methylphenidate may have positive effects on social behaviors in children with PDD and hyperactivity.

PMID:
18752063
[PubMed - indexed for MEDLINE]
PMCID:
PMC4374624
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer Icon for PubMed Central
    Loading ...
    Write to the Help Desk