Cell. 2008 Aug 22;134(4):566-8.

Silencing HIV-1 In Vivo.

Source

Institute of Virology, University of Ulm, 89081 Ulm, Germany. frank.kirchhoff@uniklinik-ulm.de

Abstract

RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS.

Comment on

Cell. 2008 Aug 22;134(4):577-86.

PMID:: 18724929; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

RNA, Small Interfering

Grant Support

R01 AI067057/AI/NIAID NIH HHS/United States

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Medical

HIV/AIDS - MedlinePlus Health Information

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