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Psychiatry Res. 2008 Oct 30;161(1):109-11. doi: 10.1016/j.psychres.2008.02.012. Epub 2008 Aug 21.

Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene.

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  • 1Department of Psychiatric Science and Psychological Medicine, Sapienza University of Rome, Rome, Italy. massimo.pasquini@uniroma1.it

Abstract

We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.

PMID:
18722020
[PubMed - indexed for MEDLINE]
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