Science. 2008 Aug 22;321(5892):1040; author reply 1040.

Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry".

Source

Department of Computer Science and Engineering, University of California, San Diego, 9500 Gilman Drive, Mail Code 0404, La Jolla, CA 92093-0404, USA. ppevzner@cs.ucsd.edu

Abstract

Asara et al. (Reports, 13 April 2007, p. 280) reported sequencing of Tyrannosaurus rex proteins and used them to establish the evolutionary relationships between birds and dinosaurs. We argue that the reported T. rex peptides may represent statistical artifacts and call for complete data release to enable experimental and computational verification of their findings.

Comment on

Science. 2007 Apr 13;316(5822):280-5.

PMID:: 18719266; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Comment

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry". [Science. 2008]
Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry".
Buckley M, Walker A, Ho SY, Yang Y, Smith C, Ashton P, Oates JT, Cappellini E, Koon H, Penkman K, et al. Science. 2008 Jan 4; 319(5859):33; author reply 33.
Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry. [Science. 2007]
Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry.
Asara JM, Schweitzer MH, Freimark LM, Phillips M, Cantley LC. Science. 2007 Apr 13; 316(5822):280-5.
Reanalysis of Tyrannosaurus rex Mass Spectra. [J Proteome Res. 2009]
Reanalysis of Tyrannosaurus rex Mass Spectra.
Bern M, Phinney BS, Goldberg D. J Proteome Res. 2009 Sep; 8(9):4328-32.
Review Limitations and pitfalls in protein identification by mass spectrometry. [Chem Rev. 2007]
Review Limitations and pitfalls in protein identification by mass spectrometry.
Lubec G, Afjehi-Sadat L. Chem Rev. 2007 Aug; 107(8):3568-84. Epub 2007 Jul 24.
Review Recent developments in proteome informatics for mass spectrometry analysis. [Comb Chem High Throughput Scre...]
Review Recent developments in proteome informatics for mass spectrometry analysis.
Wright JC, Hubbard SJ. Comb Chem High Throughput Screen. 2009 Feb; 12(2):194-202.

See reviews... See all...

Cited by 6 PubMed Central articles

The evolving field of imaging mass spectrometry and its impact on future biological research. [J Mass Spectrom. 2011]
The evolving field of imaging mass spectrometry and its impact on future biological research.
Watrous JD, Alexandrov T, Dorrestein PC. J Mass Spectrom. 2011 Feb; 46(2):209-22. Epub 2011 Jan 24.
Review Integrating '-omics' and natural product discovery platforms to investigate metabolic exchange in microbiomes. [Curr Opin Chem Biol. 2011]
Review Integrating '-omics' and natural product discovery platforms to investigate metabolic exchange in microbiomes.
Yang JY, Karr JR, Watrous JD, Dorrestein PC. Curr Opin Chem Biol. 2011 Feb; 15(1):79-87. Epub 2010 Nov 17.
Review Proteogenomics to discover the full coding content of genomes: a computational perspective. [J Proteomics. 2010]
Review Proteogenomics to discover the full coding content of genomes: a computational perspective.
Castellana N, Bafna V. J Proteomics. 2010 Oct 10; 73(11):2124-35. Epub 2010 Jul 8.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by ma...
Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry".
Science. 2008 Aug 22 ;321(5892):1040; author reply 1040.

PubMed
High-quality binary protein interaction map of the yeast interactome network.
High-quality binary protein interaction map of the yeast interactome network.
Science. 2008 Oct 3 ;322(5898):104-10. Epub 2008 Aug 21 .

PubMed
Interactions between eIF4AI and its accessory factors eIF4B and eIF4H.
Interactions between eIF4AI and its accessory factors eIF4B and eIF4H.
RNA. 2008 Oct ;14(10):2136-48. Epub 2008 Aug 21 .

PubMed
Multiplex enzyme assay screening of dried blood spots for lysosomal storage diso...
Multiplex enzyme assay screening of dried blood spots for lysosomal storage disorders by using tandem mass spectrometry.
Clin Chem. 2008 Oct ;54(10):1725-8. Epub 2008 Aug 21 .

PubMed
Identification of virulence determinants in uropathogenic Proteus mirabilis usin...
Identification of virulence determinants in uropathogenic Proteus mirabilis using signature-tagged mutagenesis.
J Med Microbiol. 2008 Sep ;57(Pt 9):1068-78.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: