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Respir Care. 2008 Sep;53(9):1208-16.

Neuropsychiatric function in chronic lung disease: the role of pulmonary rehabilitation.

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  • 1Department of Psychology, Ohio State University, 1835 Neil Avenue, 145 Psychology Building, Columbus OH 43210, USA.


Chronic lung disease is associated with increased psychological distress (especially anxiety and depression) and neuropsychological impairments (primarily in flexible problem-solving and information-sequencing), which decrease quality of life, disease management, and survival. This review summarizes current data regarding the prevalence of neuropsychiatric disorders, the assessment tools commonly used to measure and monitor neuropsychiatric symptoms, the effect of pulmonary rehabilitation on neuropsychiatric symptoms, the mechanisms by which exercise rehabilitation may influence neuropsychiatric functioning, and the clinical implications of the data.

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