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Langmuir. 2008 Sep 16;24(18):9929-32. doi: 10.1021/la800948w. Epub 2008 Aug 19.

Photochemical modification and patterning of SU-8 using anthraquinone photolinkers.

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  • 1Department of Micro and Nanotechnology, Technical University of Denmark, DTU Nanotech, Kongens Lyngby, Denmark. Gabriela.Blagoi@nanotech.dtu.dk

Abstract

Bioactive protein patterns and microarrays achieved by selective localization of biomolecules find various applications in biosensors, bio-microelectromechanical systems (bio-MEMS), and in basic protein studies. In this paper we describe simple photochemical methods to fabricate two-dimensional patterns on a Novolac A derivative polymer (SU-8) and, subsequently, their functionalization with biomolecules. Anthraquinone (AQ) derivatives are used to chemically modify and pattern SU-8 surfaces. Features as small as 20 mum are obtained when using uncollimated light. The X-Y spatial resolution of micropatterned AQ molecules is improved to 1.5 mum when a collimated light source is used. This micropatterning process will be important for the functionalization of MEMS-based biosensors. The method saves several processing steps and can be integrated in cleanroom fabrication thus avoiding contamination of the sensor surfaces.

PMID:
18710270
[PubMed - indexed for MEDLINE]
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