Knowledge based prediction of ligand binding modes...[J Med Chem. 2008] - PubMed Result

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Click to change filter selection through MyNCBI.

1: J Med Chem. 2008 Sep 11;51(17):5149-71. Epub 2008 Aug 19. Links

Knowledge based prediction of ligand binding modes and rational inhibitor design for kinase drug discovery.

Ghose AK, Herbertz T, Pippin DA, Salvino JM, Mallamo JP.

Department of Medicinal Chemistry, Cephalon, Inc., 145 Brandywine Parkway, West Chester, Pennsylvania 19380, USA. aghose@cephalon.com

PMID: 18710211 [PubMed - indexed for MEDLINE]

Related articles

The effect of a tightly bound water molecule on scaffold diversity in the computer-aided de novo ligand design of CDK2 inhibitors.
J Mol Model. 2006 Mar; 12(4):422-31. Epub 2005 Dec 23.

[J Mol Model. 2006]
Outliers in SAR and QSAR: 2. Is a flexible binding site a possible source of outliers?
J Comput Aided Mol Des. 2007 Aug; 21(8):421-35. Epub 2007 Jul 24.

[J Comput Aided Mol Des. 2007]
Rational design of inhibitors that bind to inactive kinase conformations.
Nat Chem Biol. 2006 Jul; 2(7):358-64.

[Nat Chem Biol. 2006]
ReviewStructural biology contributions to tyrosine kinase drug discovery.
Curr Opin Cell Biol. 2009 Apr; 21(2):280-7. Epub 2009 Feb 7.

[Curr Opin Cell Biol. 2009]
ReviewThe use of computational methods in the discovery and design of kinase inhibitors.
Curr Pharm Des. 2002; 8(17):1527-45.

[Curr Pharm Des. 2002]
» See reviews... | » See all...

Recent Activity

Clear Turn Off Turn On

Knowledge based prediction of ligand binding modes and rational inhibitor design for kinas...Knowledge based prediction of ligand binding modes and rational inhibitor design for kinase drug discovery.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show