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Psychiatry Res. 2008 Oct 30;164(1):73-6. doi: 10.1016/j.pscychresns.2007.12.010. Epub 2008 Aug 15.

The MAO-A genotype does not modulate resting brain metabolism in adults.

Author information

  • 1Medical Department, Brookhaven National Laboratory, Upton, New York 11973, United States. nellyklein@bnl.gov

Abstract

Variation in the monoamine-oxidase-A (MAO-A) gene has been associated with volumetric changes in corticolimbic regions with differences in their response to relevant emotional tasks. Here we show no changes in baseline regional brain metabolism as a function of genotype indicating that, unchallenged, corticolimbic activity is not modulated by the MAO-A genotype.

PMID:
18706791
[PubMed - indexed for MEDLINE]
PMCID:
PMC2596889
Free PMC Article

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