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J Clin Microbiol. 2008 Oct;46(10):3510-3. doi: 10.1128/JCM.01512-08. Epub 2008 Aug 13.

Dynamics of the mucosa-associated flora in ulcerative colitis patients during remission and clinical relapse.

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  • 1Institute for Clinical Molecular Biology, Christian Albrechts University Kiel, Schittenhelmstr. 12, 24105 Kiel, Germany.

Abstract

The colonic mucosa-associated flora (MAF) in patients with active ulcerative colitis (UC) (n = 13) was investigated by examining 16S rRNA gene signatures during remission and relapse against levels for controls (n = 5). Baseline reduction, temporal instability, and decrease of bacterial richness toward relapse were observed for UC patients, whereas the MAF for controls was stable over time.

PMID:
18701655
[PubMed - indexed for MEDLINE]
PMCID:
PMC2566070
Free PMC Article
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