Your browser version may not work well with NCBI's Web applications. More information here...
1: Dermatol Online J. 2008 Feb 28;14(2):11.Click here to read Links

Bullous mycosis fungoides: a case report.

Kamran B, Fatemeh M, Ahmadreza R, Azita N.

Departement of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Mycosis fungoides (MF) on extremely rare occasions is associated with vesiculobullous eruptions. We describe a 74-year-old man with previous documented histopathologic diagnosis of poikilodermic-type MF who recently developed flaccid acral bullae on erythematous MF plaques and on normal appearing skin. Histopathology and direct immunofluorescent studies revealed extensive lichenoid changes with intraepidermal bullae. Atypical lymphocyte infiltration was present at the dermoepidermal junction, in bulla fluid, and on the peripheral blood smear, but in lymph node and bone marrow tissue specimens atypical lymphocytes were absent. The plausible cause of these blister formations in cutaneous lymphoma bullosa may be from excessive epidermotropism or toxicity of the tumoral infiltrate.

PMID: 18700114 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Chlorambucil (Leukeran® )

    Your doctor has ordered the drug chlorambucil to help treat your illness. The drug can be taken by mouth in tablet form.

  • Source: AHFS Consumer Medication Information