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    J Am Acad Child Adolesc Psychiatry. 2008 Oct;47(10):1189-1196.

    Attention Bias Toward Threat in Pediatric Anxiety Disorders.

    Roy AK, Vasa RA, Bruck M, Mogg K, Bradley BP, Sweeney M, Bergman RL, McClure-Tone EB, Pine DS; THE CAMS TEAM.

    Dr. Roy is with the NYU Child Study Center, New York University School of Medicine; Drs. Vasa and Bruck are with the Johns Hopkins School of Medicine; Drs. Mogg and Bradley are with the School of Psychology at the University of Southampton; Dr. Sweeney is with the New York State Psychiatric Institute, New York; Dr. Bergman is with the Department of Psychiatry and Biobehavioral Science, University of California-Los Angeles; Dr. McClure-Tone is with the Department of Psychology, Georgia State University; and Dr. Pine is with the Section on Development and Affective Neuroscience, National Institute of Mental Health.

    OBJECTIVE:: To examine attention bias toward threat faces in a large sample of anxiety-disordered youths using a well-established visual probe task. METHOD:: Study participants included 101 children and adolescents (ages 7-18 years) with generalized anxiety disorder, social phobia, and/or separation anxiety disorder enrolled in a multisite anxiety treatment study. Nonanxious youths (n = 51; ages 9-18 years) were recruited separately. Participants were administered a computerized visual probe task that presents pairs of faces portraying threat (angry), positive (happy), and neutral expressions. They pressed a response key to indicate the spatial location of a probe that replaced one of the faces on each trial. Attention bias scores were calculated from response times to probes for each emotional face type. RESULTS:: Compared to healthy youths, anxious participants demonstrated a greater attention bias toward threat faces. This threat bias in anxious patients did not significantly vary across the anxiety disorders. There was no group difference in attention bias toward happy faces. CONCLUSIONS:: These results suggest that pediatric anxiety disorders are associated with an attention bias toward threat. Future research may examine the manner in which cognitive bias in anxious youths changes with treatment.

    PMID: 18698266 [PubMed - as supplied by publisher]

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