The open source software tools developed at UCLA are the informatics infrastructure supporting translational research efforts of the 11 National Cancer Institutes Prostate SPORE sites. The Codebook is a caBIG compliant application that manages PHI (e.g. names, medical record numbers, etc.) separately from research data. Research data are collected using a flexible clinical trials management suite called pTracker. Our poster will present how these two applications are implemented and function in this prospective multi-center study.