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Joint Bone Spine. 2008 Oct;75(5):606-9. doi: 10.1016/j.jbspin.2007.08.012. Epub 2008 Aug 6.

Complete reversal of tumoral calcinosis after subtotal parathyroidectomy in a hemodialysis patient.

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  • 1Service de Rhumatologie Hôpital Fattouma Bourguiba de Monastir, Monastir 5000, Tunisie. mohamed_youn@yahoo.fr

Abstract

INTRODUCTION:

Tumoral calcinosis is a rare complication of chronic hemodialysis whose mechanism is incompletely understood. The treatment is challenging and should target the main precipitating factors, most notably secondary hyperparathyroidism and calcium-phosphate (Ca x P) product elevation.

CASE REPORT:

In this 41-year-old patient, tumoral calcinosis developed in the right hip and subacromial bursa of the right shoulder after 3 years of chronic hemodialysis. Laboratory tests showed hyperparathyroidism with Ca x P elevation. Subtotal parathyroidectomy was performed. Eight months later, there was no evidence of tumoral calcinosis at either of the previously affected sites.

CONCLUSION:

The effectiveness of parathyroidectomy in our patient underlies the key role played by secondary hyperparathyroidism in the pathogenesis of tumoral calcinosis complicating hemodialysis.

PMID:
18693124
[PubMed - indexed for MEDLINE]
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