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J Clin Gastroenterol. 2008 Sep;42 Suppl 3 Pt 2:S163-7. doi: 10.1097/MCG.0b013e31817dbd62.

Interactomics in the human intestine: Lactobacilli and Bifidobacteria make a difference.

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  • 1Microbiology Department, TNO Quality of Life, Zeist, The Netherlands. rolf.boesten@wur.nl

Abstract

Scientific evidence that supports a correlation between our intestinal microbiota and health status has caused significant interest in microbe-host interaction studies. It has generated a paradigm shift from analyzing pathogens to that involving commensal and probiotic bacteria. This review summarizes the interaction mechanisms described for Lactobacilli and Bifidobacteria based on recent omics-based developments. This information is expected to provide new avenues for further unravelling the set of interactions that includes the interactome of microbial and host cells.

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