Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cell Stem Cell. 2008 Aug 7;3(2):125-6. doi: 10.1016/j.stem.2008.07.006.

A niche-defying feat: induced oligoneogenesis in the adult dentate gyrus.

Author information

  • 1Department of Neurology, University of Rochester Medical Center, Rochester, NY 14580, USA. steven_goldman@urmc.rochester.edu

Abstract

In a recent paper in Nature Neuroscience, Jessberger et al. (2008) report that overexpression of ASCL1 (mash1) directs adult hippocampal progenitors to adopt an oligodendrocytic fate. The effect is specific to the hippocampal niche in vivo, indicating that cell-autonomous and niche-defined factors collaborate to instruct cell fate choices.

PMID:
18682232
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk