Opt Express. 2008 Aug 4;16(16):12227-38.

Low-coherent quantitative phase microscope for nanometer-scale measurement of living cells morphology.

Yamauchi T, Iwai H, Miwa M, Yamashita Y.

Source

Hamamatsu Photonics K. K., 5000 Hirakuchi, Hamamatsu-City, Shizuoka-Pref. 434-8601, Japan. t-yamauchi@crl.hpk.co.jp

Abstract

We have developed a Linnik-type interference microscope provided with a low-coherent light source to obtain topographic images of an intact cellular membrane on a nanometer scale. Our technique is based on measurement of the interference between light reflected from the cell surface and a reference beam. The results show full field surface topography of cultured cells and reveal an intrinsic membrane motion of tens of nanometers.

PMID:: 18679500; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Evaluation Studies

MeSH Terms

LinkOut - more resources

Full Text Sources

Optical Society of America - PDF

Supplemental Content

Save items

Related citations in PubMed

Full-field quantitative phase imaging by white-light interferometry with active phase stabilization and its application to biological samples. [Opt Lett. 2006]
Full-field quantitative phase imaging by white-light interferometry with active phase stabilization and its application to biological samples.
Li X, Yamauchi T, Iwai H, Yamashita Y, Zhang H, Hiruma T. Opt Lett. 2006 Jun 15; 31(12):1830-2.
Full-field swept-source phase microscopy. [Opt Lett. 2006]
Full-field swept-source phase microscopy.
Sarunic MV, Weinberg S, Izatt JA. Opt Lett. 2006 May 15; 31(10):1462-4.
Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry. [Opt Lett. 2004]
Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry.
Iwai H, Fang-Yen C, Popescu G, Wax A, Badizadegan K, Dasari RR, Feld MS. Opt Lett. 2004 Oct 15; 29(20):2399-401.
Review Fluorescence interferometry: principles and applications in biology. [Ann N Y Acad Sci. 2008]
Review Fluorescence interferometry: principles and applications in biology.
Bilenca A, Cao J, Colice M, Ozcan A, Bouma B, Raftery L, Tearney G. Ann N Y Acad Sci. 2008; 1130:68-77.
Review Optical coherence tomography using rapidly swept lasers. [Conf Proc IEEE Eng Med Biol So...]
Review Optical coherence tomography using rapidly swept lasers.
Yun SH. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:125-8.

See reviews... See all...

Cited by 1 PubMed Central article

Improved phase sensitivity in spectral domain phase microscopy using line-field illumination and self phase-referencing. [Opt Express. 2009]
Improved phase sensitivity in spectral domain phase microscopy using line-field illumination and self phase-referencing.
Yaqoob Z, Choi W, Oh S, Lue N, Park Y, Fang-Yen C, Dasari RR, Badizadegan K, Feld MS. Opt Express. 2009 Jun 22; 17(13):10681-7.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Low-coherent quantitative phase microscope for nanometer-scale measurement of li...
Low-coherent quantitative phase microscope for nanometer-scale measurement of living cells morphology.
Opt Express. 2008 Aug 4 ;16(16):12227-38.

PubMed
The role of the transcription factor AP-1 in colitis-associated and beta-catenin...
The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Oncogene. 2008 Oct 16 ;27(47):6102-9. Epub 2008 Aug 4 .

PubMed
The effect of fish oil supplementation on heart rate in healthy Danish infants.
The effect of fish oil supplementation on heart rate in healthy Danish infants.
Pediatr Res. 2008 Dec ;64(6):610-4.

PubMed
Early-onset dementia is associated with higher mortality.
Early-onset dementia is associated with higher mortality.
Dement Geriatr Cogn Disord. 2008 ;26(2):147-52. Epub 2008 Aug 4 .

PubMed
Proximal and distal influences on hip and knee kinematics in runners with patell...
Proximal and distal influences on hip and knee kinematics in runners with patellofemoral pain during a prolonged run.
J Orthop Sports Phys Ther. 2008 Aug ;38(8):448-56. Epub 2008 Aug 1 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: