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1: Genome Biol. 2008;9(7):227. Epub 2008 Jul 28.Click here to read Links

Engineering a DNA damage response without DNA damage.

Yeung M, Durocher D.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University Avenue, Toronto, ON, M5G 1X5 Canada.

Recent work has achieved the feat of activating the DNA damage checkpoint in the absence of DNA damage, revealing the importance of protein-chromatin associations for the activation, amplification and maintenance of the DNA damage response.

PMID: 18671832 [PubMed - indexed for MEDLINE]

PMCID: PMC2530863 [Available on 2009/07/28]