Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia

J Pediatr Psychol. 2009 Apr;34(3):317-27. doi: 10.1093/jpepsy/jsn080. Epub 2008 Jul 30.

Abstract

Objective: To examine the role of executive function in coping and behavioral outcomes in childhood acute lymphocytic leukemia (ALL) survivors.

Methods: We examined associations among several domains of executive function (working memory, behavioral inhibition, cognitive flexibility, and self-monitoring), coping, and emotional/behavioral problems in 30 children and adolescents ages 10- to 20-years old who completed treatment for ALL and 30 healthy controls matched on age and sex.

Results: We found partial support for our hypothesis that performance on executive function measures is associated with strategies used to cope with stress, and emotional and behavioral problems in ALL survivors.

Conclusions: Findings suggest that executive function impairment may be associated with difficulties in coping and emotion regulation in a subgroup of children treated for ALL. Directions for future research on executive function deficits and coping skills in survivors of pediatric ALL are suggested.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Psychological*
  • Adolescent
  • Case-Control Studies
  • Child
  • Cognition*
  • Emotions*
  • Female
  • Humans
  • Male
  • Neuropsychological Tests / statistics & numerical data
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / psychology*
  • Stress, Psychological / etiology*
  • Survivors / psychology*
  • Young Adult