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Vet Clin North Am Equine Pract. 2008 Aug;24(2):285-97, vi. doi: 10.1016/j.cveq.2008.03.004.

Blood proteins and inflammation in the horse.

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  • 1Department of Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA.


Activation of the host response to infection, the "acute-phase response," is a highly organized physiologic reaction that includes changes in concentrations of plasma acute-phase proteins (APPs). The APPs are increasingly being used as markers for prognosis and monitoring response to therapy along with general determinants of equine health. Use of APPs in veterinary medicine is becoming more widespread as more commercial diagnostic kits are being validated. This article reviews the salient features of APPs and examines their current application and potential utility in equine inflammatory disorders.

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