Lab Chip. 2008 Aug;8(8):1258-61. Epub 2008 Jul 1.

Microfluidic based single cell microinjection.

Source

Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA. aadamo@mit.edu

Abstract

We report a microfluidic based approach for single cell microinjection in which fluid streams direct a cell onto a fixed microneedle in contrast to moving a microneedle towards an immobilized cell, as done in conventional methods. The approach simplifies microinjection and offers the potential for flow through automated microinjection of cells.

PMID:: 18651065; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Grant Support

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Research Support, N.I.H., Extramural

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Grant Support

P50-GM68762/GM/NIGMS NIH HHS/United States

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