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Clin Lymphoma Myeloma. 2008 Jun;8(3):188-90. doi: 10.3816/CLM.2008.n.025.

Association between renal cell carcinoma and plasma cell dyscrasias: a case series of six patients.

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  • 1St Vincent's Comprehensive Cancer Center, New York, NY 10011, USA.


Multiple malignancies in the same patient are unusual. This is particularly true for patients with hematologic malignancies who have a concomitant solid tumor. We report the unexpectedly higher frequency of renal cell carcinoma (RCC) associated with plasma cell dyscrasias. We report 6 cases of RCC in our institutional database of 600 patients with plasma cell dyscrasias over the past 10 years. We discuss the possible mechanisms that predisposed these patients to a secondary malignancy.

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