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PLoS One. 2008 Jul 23;3(7):e2739. doi: 10.1371/journal.pone.0002739.

Evidence of henipavirus infection in West African fruit bats.

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  • 1Institute of Zoology, Zoological Society of London, London, United Kingdom.

Abstract

Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27-51%) and Hendra (22%, 95% CI: 11-33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa.

PMID:
18648649
[PubMed - indexed for MEDLINE]
PMCID:
PMC2453319
Free PMC Article
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