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Gut. 1991 Feb;32(2):225-6.

IgA nephropathy in non-cirrhotic portal hypertension.

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  • 1University Department of Gastroenterology Manchester Royal Infirmary.

Abstract

Renal glomerular changes are a well recognised complication of cirrhosis and are frequently characterised by mesangial IgA deposition. We report a patient with non-cirrhotic portal hypertension who developed IgA nephropathy and a nephrotic syndrome with renal histological changes classically associated with cirrhosis. Splenectomy with resection of a splenic artery aneurysm resulted in remission of the nephrotic syndrome. This case illustrates the factors which contribute to the pathogenesis of IgA nephropathy in liver disease.

PMID:
1864547
[PubMed - indexed for MEDLINE]
PMCID:
PMC1378814
Free PMC Article
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