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FEBS Lett. 1991 Jul 29;286(1-2):47-54.

Shuffled domains in extracellular proteins.

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  • 1Central Institute of Molecular Biology, Berlin, Germany.


A comprehensive list of domains in extracellular mosaic proteins is presented. About 40 domains were distinguished by consensus patterns. A subsequent sequence database search recognized these domains in more than 200 extracellular proteins. The results point to a structural network, which may also represent the molecular basis for a complex coordination of various functions within the world of extracellular proteins.

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