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Trends Plant Sci. 2008 Aug;13(8):405-8. doi: 10.1016/j.tplants.2008.05.010. Epub 2008 Jul 17.

BFA effects are tissue and not just plant specific.

Author information

  • 1Department of Cell Biology, Heidelberg Institute for Plant Sciences, University of Heidelberg, 69120 Heidelberg, Germany.

Abstract

Brefeldin A (BFA) is one of the most popular drugs used by researchers for studies on secretion and endocytosis because it interferes with specific vesicle coat proteins via action on a guanine nucleotide exchange factor. Due to its range of morphological effects on the Golgi apparatus in a variety of plant tissues, we believe that there is more to the BFA response than the primary molecular targets so far identified.

PMID:
18640067
[PubMed - indexed for MEDLINE]
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