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J Nat Prod. 2008 Aug;71(8):1327-30. doi: 10.1021/np070532u. Epub 2008 Jul 19.

Cucurbitane-type triterpenoids from the stems of momordica charantia.

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  • 1Graduate Institute of Biotechnology, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan, Republic of China.

Abstract

Four new cucurbitane-type triterpenes, cucurbita-5,23(E)-diene-3beta,7beta,25-triol (1), 3beta-acetoxy-7beta-methoxycucurbita-5,23(E)-dien-25-ol (2), cucurbita-5(10),6,23(E)-triene-3beta,25-diol (5), and cucurbita-5,24-diene-3,7,23-trione (6), together with four known triterpenes, 3beta,25-dihydroxy-7beta-methoxycucurbita-5,23(E)-diene (3), 3beta-hydroxy-7beta,25-dimethoxycucurbita-5,23(E)-diene (4), 3beta,7beta,25-trihydroxycucurbita-5,23(E)-dien-19-al (7), and 25-methoxy-3beta,7beta-dihydroxycucurbita-5,23(E)-dien-19-al (8), were isolated from the methyl alcohol extract of the stems of Momordica charantia. The structures of the new compounds were elucidated by spectroscopic methods.

PMID:
18637688
[PubMed - indexed for MEDLINE]
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