Send to:

Choose Destination
See comment in PubMed Commons below
Hum Mol Genet. 2008 Apr 15;17(R1):R23-7. doi: 10.1093/hmg/ddn050.

Molecular basis of pluripotency.

Author information

  • 1Division of Pediatric Hematology/Oncology, Children's Hospital Boston, Dana Farber Cancer Institute, Boston, MA 02115, USA.


Embryonic stem (ES) cells are pluripotent and capable of self-renewal, thus holding promise for regenerative medicine. Recent studies have begun to provide insights into the molecular mechanisms underlying pluripotency and self-renewal. In this article, we discuss the roles of transcriptional regulation, epigenetic regulation and miRNAs in the maintenance of pluripotency and the differentiation of ES cells.

[PubMed - indexed for MEDLINE]
Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk