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    Dermatol Online J. 2008 Apr 15;14(4):9.

    Argyria attributed to silvadene application in a patient with dystrophic epidermolysis bullosa.

    Browning JC, Levy ML.

    Department of Dermatology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA. johnbrowningmd@yahoo.com

    Argyria is most commonly reported in association with prolonged ingestion of silver-containing medicaments. This case illustrates the rather unique case of development of argyria following application of silver sulfadiazine in a patient with epidermolysis bullosa.

    PMID: 18627731 [PubMed - indexed for MEDLINE]

    Supplemental Content

    Patient drug information

    • Sulfadiazine (Microsulfon®)

      Sulfadiazine, a sulfa drug, eliminates bacteria that cause infections, especially urinary tract infections. Antibiotics will not work for colds, flu, or other viral infections.

    • Silver Sulfadiazine (Silvadene®, SSD Cream®, Thermazene®)

      Silver sulfadiazine, a sulfa drug, is used to prevent and treat infections of second- and third-degree burns. It kills a wide variety of bacteria.