Phys Med Rehabil Clin N Am. 2008 Aug;19(3):573-89, x.

Nutrition and dietary supplements in motor neuron disease.

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Division of Neurology, University of California San Francisco-Fresno, Fresno, CA, USA. jrosenfeld@carolina.rr.com

Abstract

Compromised nutrition leading to weight loss is a common and significant problem in the amyotrophic lateral sclerosis (ALS) patient population. The benefit of aggressive and early nutritional therapy can profoundly influence the disease course, quality of life, and survival. This article reviews the role of nutrition, both as sustenance and treatment for patients who have ALS. Self-medication with dietary supplements has become increasingly popular within this patient population. Despite their popularity, the efficacy of these compounds has been largely unsupported by formal clinical trials. Available data will be highlighted to provide a basis upon which to advise patients requesting guidance.

PMID:: 18625417; [PubMed - indexed for MEDLINE]
PMCID:: PMC2631353

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R01 AT000967-03/AT/NCCAM NIH HHS/United States

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