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Curr Opin Genet Dev. 2008 Aug;18(4):330-6. doi: 10.1016/j.gde.2008.06.005. Epub 2008 Jul 30.

Skeletal muscle stem cells.

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  • 1Pasteur Institute, CNRS URA 2578, 28 rue du Dr Roux, 75015 Paris, France.


In this review we shall discuss recent publications on the heterogeneity of muscle stem cells, signaling pathways that affect their behaviour and regulatory mechanisms that underlie their myogenic fate, with reference to insights provided by work on skeletal muscle formation in the embryo as well as the adult, with the mouse as a model of reference.

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