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    Br J Ophthalmol. 2008 Sep;92(9):1257-60. Epub 2008 Jul 11.

    Filling in at partially deafferented visual cortex.

    Alvarenga DP, Couto MF, Pessoa VF.

    Neuroscience and Behavior Laboratory, Institute of Biology, Brasilia University, 70910900, Brasilia, Brazil. oftalmop@terra.com.br

    METHODS: Perceptual visual filling in at the corresponding area of toxoplasmic retinochoroiditis scotomas in the fellow eye was studied in 14 patients. Targets were programmed to appear inside the scotoma corresponding area in the fellow eye, and at two control points. RESULTS: The results showed faster perceptual filling-in latencies (p<0.0001) in the scotoma corresponding area than at the control points. CONCLUSIONS: Perceptual filling in is facilitated at the corresponding area of retinal scotomas. The neural mechanisms of this visual facilitation might be similar to those found following somatosensory cortex partial deafferentation.

    PMID: 18621793 [PubMed - indexed for MEDLINE]