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    AIDS. 2008 Jul 31;22(12):1513-5.

    Serum alpha-fetoprotein predicts virologic response to hepatitis C treatment in HIV coinfected patients.

    Carrat F, Bedossa P, Lunel-Fabiani F, Morand P, Pialoux G, Piroth L, Salmon-Céron D, Bani-Sadr F, Perronne C, Cacoub P, Pol S.

    UPMC-Paris6, UMR-S707, INSERM, UMR-S707, Saint-Antoine Hospital, Assistance Publique Hôpitaux de Paris, France. carrat@u707.jussieu.fr

    We explored the link between serum alpha-fetoprotein levels and virologic response in 383 HIV-hepatitis C virus coinfected patients. A low alpha-fetoprotein level (<5.0 ng/ml) was an independent predictor of sustained virologic response (odds ratio = 1.83; 95% confidence interval 1.05-3.20). Serum alpha-fetoprotein measurement should be integrated in the pretreatment assessment of prognostic factors of a virologic response.

    PMID: 18614875 [PubMed - indexed for MEDLINE]

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