Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cell. 2008 Jul 11;134(1):14-6. doi: 10.1016/j.cell.2008.06.041.

Interchromosomal huddle kickstarts antiviral defense.

Author information

  • 1The Babraham Institute, Laboratory of Chromatin and Gene Expression, Babraham Research Campus, Cambridge, UK.

Abstract

Long-distance chromosomal interactions are emerging as a potential mechanism of gene expression control. In this issue, Apostolou and Thanos (2008) describe how viral infection elicits interchromosomal associations between the interferon-beta (IFN-beta) gene enhancer and DNA binding sites of the transcription factor NF-kappaB, resulting in the initiation of transcription and an antiviral response.

Comment on

PMID:
18614003
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk