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Division of Pediatric Endocrinology, Child Health Evaluation and Research Unit, University of Michigan, Campus Box 5456, Ann Arbor, MI 48109-5456, USA. joyclee@umich.edu
Despite significant increases in prevalence rates of childhood obesity in the United States during the past 2 decades, rates of type 2 diabetes mellitus among children at the population level have not followed a similar trajectory as those in adults. In this review, hypotheses for the contrasting findings in children compared with adults are explored, as are possible links between the trends in childhood obesity rates and increases in type 2 diabetes among young adults in the United States. This review concludes with observations about the profound policy implications from current patterns of type 2 diabetes among youth and particularly young adults and a proposed research agenda regarding childhood obesity and type 2 diabetes risk over the life course.
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