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Isr Med Assoc J. 2008 May;10(5):381-5.

Hydrogen fluoride--the protoplasmic poison.

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  • 1CBRN Medical Branch, Medical Corps, Israel Defense Force.


HF is a corrosive mineral acid. It has extremely harmful systemic effects through any route of exposure. In dilute solutions the onset of symptoms is latent. It is important for caregivers to remember that HF has distinct clinical signs and a specific antidote, namely calcium gluconate. The industrial use of HF heightens the importance of being prepared for possible exposures. The emergency medical teams should be familiar with its symptoms, should possess the proper protective means and should be ready to respond properly in case of emergency.

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