Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Am J Ophthalmol. 2008 Oct;146(4):534-542. doi: 10.1016/j.ajo.2008.05.030. Epub 2008 Jul 7.

Assessment of the use of anterior segment optical coherence tomography in microbial keratitis.

Author information

  • 1Southampton Eye Unit, Southampton General Hospital, Southampton, United Kingdom.

Abstract

PURPOSE:

To investigate the imaging capabilities of anterior segment optical coherence tomography (AS OCT) in microbial keratitis and to assess whether measurements of the quantitative parameters, infiltrate thickness and corneal thickness, were possible.

DESIGN:

Prospective, noncomparative, observational case series.

METHODS:

The study was conducted at a university hospital clinical setting. Seven patients (eyes) with suspected microbial keratitis underwent standard clinical examination and treatment based on slit-lamp clinical findings. AS OCT scanning was performed on presentation and at two follow-up appointments. All scans were carried out with the scanning beam passing through the center of the infiltration and at a specific meridian. Examination was carried out by the same operator.

RESULTS:

Corneal infiltration was imaged as a hyperreflective area in the corneal stroma on high-resolution AS OCT scans. Retrocorneal pathologic features and anterior chamber inflammatory cells could be imaged. Corneal and infiltrate thickness could be measured with calipers in six cases. In one case, corneal and infiltrate thickness could not be measured because of a thick inflammatory plaque attached to the endothelium. In this case, the width of the plaque was measured on serial scans.

CONCLUSIONS:

AS OCT imaging provides a range of parameters that can be used to assess microbial keratitis and the treatment response objectively.

PMID:
18602080
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk