Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Cell Biol. 2008 Jul;10(7):757-9. doi: 10.1038/ncb0708-757.

Breaking down EMT.

Author information

  • 1IBDML, UMR6216 CNRS-Université de la Méditerranée, Campus de Luminy, 13288 Marseille Cedex 09, France.

Abstract

Epithelial-mesenchymal transition, in which epithelial cells lose their polarity and become motile mesenchymal cells, occurs during development and marks a key step in tumour progression towards metastasis. Most studies of this process have focused on the disassembly of adherens junctions, but regulation of basement membrane breakdown by a pathway involving RhoA and microtubules may be equally important.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk