Am J Obstet Gynecol. 1976 Oct 15;126(4):445-8.

Blood as a potential vehicle for the cytomegaloviruses.

Abstract

This study analyzed transfused blood as a potential vehicle for infectious cytomegalovirus (CMV) particles. A total of 207 patients who received a total number of 897 units of blood were monitored. A complement-fixing antibody titer of 1:8, as determined by micro-titer technique, was observed in 14.8 per cent of the blood units. A total of 140 individuals in this study were serosusceptible. Eighty-six serosusceptible individuals did not receive blood containing complement-fixing CMV antibodies. In this patient population three instances of seroconversion were identified. Among the 54 serosusceptible individuals who received at least one unit of blood whose complement-fixing titer to the AD-169 strain of CMV was 1:8 or greater, 13 seroconversions were observed.

PMID:: 185907; [PubMed - indexed for MEDLINE]

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Research Support, U.S. Gov't, P.H.S.

MeSH Terms

Substances

Antibodies, Viral

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Cited by 3 PubMed Central articles

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