Cell Metab. 2008 Jul;8(1):4-5.

The ongoing saga of sirtuins and aging.

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Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA. kaeber@u.washington.edu

Abstract

Sirtuins are known to slow aging in simple eukaryotes; however, viewing mammalian sirtuins as antiaging proteins may be overly simplistic. In this issue of Cell Metabolism, Li et al. (2008) provide evidence that SirT1 has properties consistent with both pro- and antiaging functions in mice.

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Cell Metab. 2008 Jul;8(1):38-48.

PMID:: 18590685; [PubMed - indexed for MEDLINE]

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P50 AG005136-25/AG/NIA NIH HHS/United States

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Cited by 4 PubMed Central articles

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