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    Semin Pediatr Surg. 2008 Aug;17(3):154-60.

    Embryology, sternal clefts, ectopia cordis, and Cantrell's pentalogy.

    Engum SA.

    Division of Pediatric Surgery, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202, USA. sengum@iupui.edu <sengum@iupui.edu>

    Sternal clefts, ectopia cordis, and Cantrell's pentalogy continue to be very rare congenital anomalies in pediatric surgery. Unfortunately, these conditions present as neonatal emergencies and demand early surgical intervention. This article reviews the embryological development of the chest wall, specific sternal defect anomalies, along with available methods of treatment.

    PMID: 18582820 [PubMed - indexed for MEDLINE]

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